Technical Problems Inherent to Intraarterial Chemotherapy in Head and Neck Cancer
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چکیده
منابع مشابه
Intraarterial chemotherapy and chemoembolization in head and neck cancer. Establishment as a neoadjuvant routine method
Over decades, local chemotherapy for head and neck cancer was a challenging treatment modality mainly for palliative use. In the last decade, a reappraisal started due to technical innovations. But a regular and safe clinical use has not been established, nor has a pharmacological rationale for this modality been given for humans. A routine intensification of effectivity by embolization in the ...
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The role of chemotherapy in the management of patients with head and neck cancer continues to evolve. Single-agent methotrexate or cisplatin, or the combination of cisplatin and infusional fluorouracil can be considered standard therapy for patients with recurrent disease. Neoadjuvant chemotherapy is being actively pursued. Although enhanced survival has not yet been demonstrated, the goal of o...
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Sulphur mustard was synthesized in 1854 and its vesicant properties described in 1887. Medical attention was focused on the chemical during World War I when its vesicant action on the skin, eyes and respiratory tract was noted in full and it was developed as a chemical weapon. It became apparent that those who survived gassing with sulphur mustard frequently developed leukopenia and in those th...
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Numerous studies have shown cisplatin-based chemotherapy to be effective in the treatment of head and neck cancer. Cisplatin/5-fluorouracil (5-FU) is the most frequently used combination regimen, but neurotoxicity, ototoxicity, and renal toxicity limit repeated dosing (for long-term treatment of responding patients) and dose intensification. In studies to date, the analogue carboplatin appears ...
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ژورنال
عنوان ژورنال: Japanese jornal of Head and Neck Cancer
سال: 1985
ISSN: 1883-9878,0911-4335
DOI: 10.5981/jjhnc1974.12.40